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Evidence suggests that low intake of omega-3 fatty acids contributes to depression

For everything else, injection is the clinically validated route

Common side effects during the adjustment period (typically the first 24 weeks): Mild nausea usually less intense than when first starting a GLP-1 medication Changes in appetite (some patients notice less appetite suppression early on at the starting 0.25 mg dose) Mild stomach discomfort, bloating, or constipation Injection site reactions Side effects that are less likely during the switch (compared to first-time GLP-1 use), but still possible: Significant vomiting less common given prior GLP-1 exposure, but possible Hypoglycemia particularly relevant for type 2 diabetes patients on insulin or sulfonylureas

The defensible statement is narrow and it is enough: there is no FDA-approved GHK-Cu drug product for any indication, and no approved injectable GHK-Cu product in any jurisdiction